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The Spinal Cord01:54

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The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
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The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Spinal Cord01:26

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The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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Related Experiment Video

Updated: Apr 14, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
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Spinal cord involvement in tuberculous meningitis.

R K Garg1, H S Malhotra1, R Gupta1

  • 1Department of Neurology, King George Medical University, Uttar Pradesh, India.

Spinal Cord
|April 22, 2015
PubMed
Summary

Tuberculous meningitis often causes severe spinal cord and nerve root issues. Current treatments for these complications are insufficient, leading to unpredictable patient outcomes.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Spinal Cord Medicine

Background:

  • Tuberculous meningitis (TBM) is a serious infection with potential neurological sequelae.
  • Spinal cord and nerve root involvement are recognized but not fully characterized complications of TBM.

Purpose of the Study:

  • To summarize the incidence and spectrum of spinal cord-related complications in patients diagnosed with tuberculous meningitis.

Main Methods:

  • An extensive literature review was conducted using Scopus, PubMed, and Google Scholar.
  • Included studies were published in English and originated from multiple countries.

Main Results:

  • TBM frequently impacts the spinal cord and nerve roots, manifesting as radiculomyelitis, tuberculomas, myelitis, syringomyelia, and vertebral tuberculosis.

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  • Neuroimaging techniques like MRI are crucial for diagnosis, revealing diffuse enhancement of the cord, nerve roots, and meninges.
  • Tuberculous spinal arachnoiditis can occur paradoxically, with high cerebrospinal fluid protein being a risk factor.
  • Conclusions:

    • Tuberculous meningitis is commonly associated with debilitating spinal cord and radicular complications.
    • Existing treatment options for these complications are currently inadequate, resulting in variable patient prognoses.