Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Bitesize bundles F-actin and influences actin remodeling in syncytial Drosophila embryo development.

The Journal of cell biology·2026

Same author

SETD2 Deficiency Drives Mitochondrial DNA Leakage and Creates a Druggable Dependency on BCL-XL in Clear Cell Renal Cell Carcinoma.

Cancer research·2026

Same author

Pharmacologic and Oncohistone Inhibition of SETD2 Converge on Genomic Instability.

Cancers·2026

Same author

Lysine demethylase 4A is a centrosome-associated protein required for centrosome integrity and genomic stability.

The FEBS journal·2025

Same author

A SETD2-CDK1-lamin axis maintains nuclear morphology and genome stability.

Nature cell biology·2025

Same author

A lateral tension model for mouse cranial neural tube closure.

bioRxiv : the preprint server for biology·2025

Same journal

AXIN1 and AXIN2 regulate the WNT-signaling landscape to promote distinct mesoderm programs.

Developmental cell·2026

Same journal

ARID1A terminates gastric regeneration to prevent cancer.

Developmental cell·2026

Same journal

Myc sustains sex-biased organ zonation in the Drosophila intestine.

Developmental cell·2026

Same journal

Two parallel neuronal circuits involving electrical synapse and DAF-7/TGF-β signaling regulate muscle autophagy in C. elegans.

Developmental cell·2026

Same journal

Menstruation: Once unspoken but now uncovered, one cell type at a time.

Developmental cell·2026

Same journal

The ALS- and FTD-associated proteins annexin A11 and CHMP2B act sequentially in plasma membrane repair.

Developmental cell·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 5, 2026

High-Sensitivity Nuclear Magnetic Resonance at Giga-Pascal Pressures: A New Tool for Probing Electronic and Chemical Properties of Condensed Matter under Extreme Conditions

High-Sensitivity Nuclear Magnetic Resonance at Giga-Pascal Pressures: A New Tool for Probing Electronic and Chemical Properties of Condensed Matter under Extreme Conditions

Published on: October 10, 2014

Crumbling under pressure.

Frank M Mason¹, Adam C Martin¹

¹Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

Developmental Cell

|April 22, 2015

Summary

This summary is machine-generated.

Organisms need tissue tension to resist gravity and maintain their shape. This study highlights how tissue tension mechanisms are crucial for resisting physical perturbations like gravity.

More Related Videos

High-pressure, High-temperature Deformation Experiment Using the New Generation Griggs-type Apparatus

High-pressure, High-temperature Deformation Experiment Using the New Generation Griggs-type Apparatus

Published on: April 3, 2018

Predicting Catalyst Extrudate Breakage Based on the Modulus of Rupture

Predicting Catalyst Extrudate Breakage Based on the Modulus of Rupture

Published on: May 13, 2018

Related Experiment Videos

Last Updated: Apr 5, 2026

High-Sensitivity Nuclear Magnetic Resonance at Giga-Pascal Pressures: A New Tool for Probing Electronic and Chemical Properties of Condensed Matter under Extreme Conditions

High-Sensitivity Nuclear Magnetic Resonance at Giga-Pascal Pressures: A New Tool for Probing Electronic and Chemical Properties of Condensed Matter under Extreme Conditions

Published on: October 10, 2014

High-pressure, High-temperature Deformation Experiment Using the New Generation Griggs-type Apparatus

High-pressure, High-temperature Deformation Experiment Using the New Generation Griggs-type Apparatus

Published on: April 3, 2018

Predicting Catalyst Extrudate Breakage Based on the Modulus of Rupture

Predicting Catalyst Extrudate Breakage Based on the Modulus of Rupture

Published on: May 13, 2018

Area of Science:

Biophysics
Developmental Biology
Mechanobiology

Background:

Organisms must maintain structural integrity against physical forces.
Gravity presents a constant physical perturbation that challenges organismal form.
Tissue tension is a key biophysical property influencing structural stability.

Purpose of the Study:

To investigate the role of tissue tension in resisting gravitational forces.
To understand the mechanisms by which organisms maintain form under physical stress.

Main Methods:

The study likely involved observing model organisms or cellular systems under varying gravitational conditions.
Analysis of cellular and tissue-level responses to mechanical stress was probably employed.
Investigating the molecular and physical underpinnings of tissue tension was central.

Main Results:

Mechanisms promoting tissue tension were identified as critical for resisting gravity.
The findings suggest a direct link between tissue tension and the ability to withstand physical perturbations.
The study provides evidence for the importance of mechanical forces in maintaining organismal form.

Conclusions:

Tissue tension is essential for organisms to counteract the effects of gravity.
Understanding these mechanisms is vital for fields like developmental biology and regenerative medicine.
The study underscores the significance of biophysical principles in biological form and function.