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[Pancreatic cancer- a curable disease]
Perparim Limani1, Panagiotis Samaras2, Mickael Lesurtel1
1Schweizerisches Hepato-Pancreato-Biliäres Zentrum und Departement Chirurgie, Universitätsspital Zürich.
Pancreatic cancer has a poor prognosis, but survival rates are improving with advanced diagnostics and multimodal treatments. Multidisciplinary care at specialized centers offers the best outcomes for patients with this challenging disease.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Oncology
Context:
- Pancreatic cancer is the seventh most common malignancy in Switzerland.
- It historically presents with a dismal prognosis and a 3-year survival rate below 3%.
Purpose:
- To review current management strategies for pancreatic cancer.
- To highlight the benefits of multidisciplinary treatment in experienced centers.
Summary:
- Significant advancements in diagnostics, staging, and multimodal therapies have improved the 5-year survival rate to over 20%.
- Surgical resection combined with adjuvant chemotherapy remains the only curative approach.
- Neoadjuvant chemotherapy is under investigation, and clinical trials offer options for advanced cases.
Impact:
- Improved patient outcomes through specialized, multidisciplinary care.
- Enhanced survival rates for pancreatic cancer patients.
- Ongoing research into novel treatment concepts for advanced disease.
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