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In-vitro Mutagenesis

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

What is Genetic Engineering?

What is Genetic Engineering?

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Related Experiment Video

Updated: Jan 21, 2026

Generation of Maternal Mutants Using zpc:cas9 Knock-in Zebrafish

Generation of Maternal Mutants Using zpc:cas9 Knock-in Zebrafish

Published on: July 22, 2025

TPC1 Knockout Knocks Out TPC1

Robert Hooper¹, Dev Churamani¹, Sean M Davidson²

¹Department of Cell and Developmental Biology, University College London, London, United Kingdom.

Molecular and Cellular Biology

|April 23, 2015

Summary

No abstract available in PubMed .

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