Closure of difficult wounds by external tissue expansion
1Flushing Hospital & Medical Center, New York, New York;
Wounds : a Compendium of Clinical Research and Practice
|April 23, 2015
Summary
Physicians face challenges with open, nonhealing wounds, especially in the elderly and diabetic populations. An external tissue expansion device effectively closes most wounds within 1-2 weeks, improving patient quality of life and reducing healthcare costs.
Area of Science:
- Wound healing
- Plastic surgery
- Geriatric medicine
Background:
- Open nonhealing wounds present significant clinical challenges.
- Elderly patients, particularly those with diabetes, are prone to difficult-to-close wounds like pressure sores and foot ulcers.
- Comorbid conditions complicate wound closure in geriatric populations.
Purpose of the Study:
- To evaluate the efficacy of an external tissue expansion device for wound closure.
- To present a method for improving the quality of life for patients with chronic wounds.
- To reduce healthcare costs associated with prolonged wound management.
Main Methods:
- Review of over 100 combined years of physician experience in wound treatment.
- Application of an external tissue expansion device for wound closure over the last 12 years.
- Comparison of outcomes with traditional methods like antibiotics, specialized dressings, growth factors, negative pressure wound therapy, and flaps.
Main Results:
- The external tissue expansion device successfully closed most wounds.
- Wound closure was typically achieved within 1 to 2 weeks.
- This method offers a faster alternative to conventional treatments.
Conclusions:
- External tissue expansion is an effective method for closing challenging wounds.
- Rapid wound closure significantly enhances patient quality of life.
- This approach offers a cost-effective solution for wound management in healthcare systems.
Related Concept Videos
Phases of Wound Repair
9.9K
Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
9.9K
Clinical Applications of Epidermal Stem Cells
3.4K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.4K
Inflammatory Response II: Inflammatory Exudate and Tissue Repair
9.5K
The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
9.5K


