Evaluating the trabecular micro-bypass stent combined with phacoemulsification compared to phacoemulsification alone
M El Wardani1, C Bergin1, F Achache1
1Department of Ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, Foundation Asile des Aveugles, Lausanne, Switzerland.
Summary
iStent implantation with phacoemulsification significantly reduced glaucoma medications compared to phacoemulsification alone. This combination therapy offers potential benefits for early to moderate glaucoma patients.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Surgical Innovation
Background:
- Glaucoma management often involves intraocular pressure (IOP) reduction and medication adherence.
- Phacoemulsification is a common cataract surgery.
- Trabecular micro-bypass stents offer a minimally invasive glaucoma surgical option.
Purpose of the Study:
- To evaluate the efficacy of iStent implantation combined with phacoemulsification.
- To compare IOP and glaucoma medication reduction with phacoemulsification alone.
Main Methods:
- Retrospective comparative study of 131 eyes with ocular hypertension/glaucoma.
- Groups: phacoemulsification alone (n=78), one iStent + phacoemulsification (n=31), two iStents + phacoemulsification (n=22).
- Postoperative assessment of IOP, visual acuity, and medication use up to 6 months.
Main Results:
- All groups showed IOP reduction; group III (two iStents) achieved statistically significant reduction (p=0.05).
- Glaucoma medication use decreased significantly in both iStent groups (II: 27%, p=0.04; III: 45%, p<0.01).
- Phacoemulsification alone showed minimal medication reduction (8%, p=0.12).
Conclusions:
- iStent implantation combined with phacoemulsification provides significant medication reduction in glaucoma patients.
- This approach may enhance patient compliance and quality of life.
- The combination therapy is a viable option for early to moderate glaucoma.
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