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Related Experiment Video

Updated: Apr 14, 2026

Dynamic Pore-scale Reservoir-condition Imaging of Reaction in Carbonates Using Synchrotron Fast Tomography
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X-ray phase-contrast tomography with a compact laser-driven synchrotron source.

Elena Eggl1, Simone Schleede2, Martin Bech3

  • 1Physik-Department und Institut für Medizintechnik, Technische Universität München, 85748 Garching, Germany; elena.eggl@ph.tum.de.

Proceedings of the National Academy of Sciences of the United States of America
|April 23, 2015
PubMed
Summary

Laser-driven compact synchrotron light sources (CLS) offer a solution for advanced X-ray imaging. This study demonstrates their successful use in multimodal X-ray tomography, outperforming conventional methods.

Keywords:
X-ray imagingdark-field tomographygrating interferometerinverse Compton X-raysphase-contrast tomography

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Area of Science:

  • Physics
  • Materials Science
  • Biomedical Imaging

Background:

  • A significant performance gap exists between conventional X-ray tubes and large synchrotron sources in terms of X-ray beam monochromaticity and brilliance.
  • Large-scale synchrotrons are inaccessible for many academic and industrial laboratories due to their size and cost.

Purpose of the Study:

  • To demonstrate the feasibility of using laser-driven compact synchrotron light sources (CLS) for advanced X-ray imaging applications.
  • To showcase the capability of CLS in performing multimodal X-ray tomography.

Main Methods:

  • Utilized a laser-driven compact synchrotron light source (CLS) generating hard X-rays via inverse Compton scattering.
  • Employed the intrinsically monochromatic and highly collimated X-ray beam from the CLS for multimodal X-ray tomography.
  • Conducted experiments using a fluid phantom and a biomedical sample (ex vivo mouse).

Main Results:

  • Successfully demonstrated multimodal X-ray tomography (phase-, dark-field, and attenuation-contrast) using a CLS-generated X-ray beam.
  • Obtained quantitative multimodal computed tomography (CT) results from a fluid phantom and a mouse sample.
  • The results from the CLS approach outperformed those from conventional methods.

Conclusions:

  • Laser-driven CLS are a viable technology for closing the performance gap in X-ray sources.
  • Quantitative multimodal CT is feasible with CLS, offering superior performance compared to traditional techniques.
  • CLS technology enables advanced X-ray imaging applications in smaller laboratory settings.