Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

368
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
368
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

4.2K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
4.2K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

5.9K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
5.9K
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

339
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
339
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

352
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
352
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

329
In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
329

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute effect of continuous perturbations of the base of support on reactive balance response.

Scientific reports·2026
Same author

Voluntary and electrically-induced muscle fatigue differently affect postural control mechanisms in unipedal stance.

Experimental brain research·2018
Same author

Redox Status of Professional Soccer Players is Influenced by Training Load Throughout a Season.

International journal of sports medicine·2016
Same author

Rapid weight loss alters muscular performance and perceived exertion as well as postural control in elite wrestlers.

The Journal of sports medicine and physical fitness·2014
Same author

Regular physical activity reduces the effects of Achilles tendon vibration on postural control for older women.

Scandinavian journal of medicine & science in sports·2014
Same author

Do epoch lengths affect adolescents' compliance with physical activity guidelines?

The Journal of sports medicine and physical fitness·2014

Related Experiment Video

Updated: Apr 14, 2026

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease
07:21

Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease

Published on: June 16, 2023

1.7K

[Specific risks of physical activity in the elderly].

T Paillard

    Revue Medicale De Liege
    |April 24, 2015
    PubMed
    Summary

    Physical activity is safe for seniors when adapted to their abilities, reducing injury risks. Proper hydration and avoiding extreme conditions are key for metabolic health in older adults.

    Area of Science:

    • Gerontology
    • Sports Medicine
    • Exercise Physiology

    Context:

    • Elderly individuals face unique health considerations regarding physical activity.
    • Maintaining physical integrity and metabolic regulation are crucial for healthy aging.

    Purpose:

    • To identify and analyze the specific risks associated with physical activity in the elderly population.
    • To provide guidance on mitigating these risks through appropriate exercise selection and preventative measures.

    Summary:

    • Physical activity risks for seniors, including injury and metabolic issues, are manageable.
    • Adapted physical activity and preventative education significantly lower accident rates in older adults.
    • Specific exercise conditions (isometric contractions, extreme temperatures) and inadequate hydration pose metabolic risks.

    More Related Videos

    Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
    07:27

    Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

    Published on: October 6, 2016

    11.0K
    Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
    12:59

    Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

    Published on: July 5, 2017

    13.4K

    Related Experiment Videos

    Last Updated: Apr 14, 2026

    Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease
    07:21

    Walk with Me Hybrid Virtual/In-Person Walking for Older Adults with Neurodegenerative Disease

    Published on: June 16, 2023

    1.7K
    Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
    07:27

    Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

    Published on: October 6, 2016

    11.0K
    Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
    12:59

    Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

    Published on: July 5, 2017

    13.4K

    Impact:

    • Promotes safer exercise participation among elderly individuals.
    • Supports the development of evidence-based guidelines for senior physical activity programs.
    • Contributes to the overall health and well-being of the aging population.