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Magnetic resonance imaging of uveitis
Charles Q Li1, Aaron A Cho, Neeraj J Edward
1Department of Radiology, University of California, San Diego, 200 West Arbor Drive #8756, San Diego, CA, 92103, USA, charlesli@alumni.upenn.edu.
Neuroradiology
|April 24, 2015
Summary
Magnetic Resonance Imaging (MRI) reveals increased uveal tract enhancement in patients with uveitis, aiding diagnosis and complication assessment. This imaging technique offers valuable insights into various uveitis etiologies and related conditions.
Area of Science:
- Ophthalmology
- Radiology
- Medical Imaging
Background:
- Uveitis involves inflammation of the uveal tract (choroid, iris, ciliary body).
- Causes can be idiopathic or linked to systemic diseases (infectious/noninfectious).
- Current imaging is largely non-radiologic, except for B-scan ultrasonography.
Purpose of the Study:
- To comprehensively review Magnetic Resonance Imaging (MRI) findings in uveitis.
- To assess MRI's utility in diagnosing and monitoring uveitis of diverse etiologies.
- To explore MRI's role in evaluating uveitis complications and differentiating from masquerade syndromes.
Main Methods:
- Review of MRI and CT scans from seven uveitis patients.
- Inclusion of clinical history for three patients.
- Analysis of etiologies including ankylosing spondylitis, relapsing polychondritis, Vogt-Koyanagi-Harada disease, sarcoidosis, and tuberculosis.
Main Results:
- All six MRI studies showed increased gadolinium enhancement of the uveal tract.
- Diffusion-weighted imaging detected restriction in uvea and subretinal effusions in one case.
- Other findings included inflammatory nodules, vitreous abnormalities, perineural/perimuscular enhancement, and uveoscleral thickening with calcification on CT.
Conclusions:
- Increased uveal tract enhancement is a frequent MRI finding in uveitis.
- MRI aids in evaluating uveitis complications.
- MRI can help distinguish uveitis from masquerade syndromes.
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