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Synthesis of some 1,2,4-triazolo [3,4-b] [1,3,4]thiadiazoles as potential anthelmintics
S M el-Khawass1, M A Khalil, A A Hazzaa
1Pharmaceutical Chemistry Department, Faculty of Pharmacy, University of Alexandria, Egypt.
Abstract:
Two novel series of triazolothiadiazole derivatives were synthesized, namely: 6-substituted-3-(4-substituted phenoxymethyl)-1,2,4-triazolo[3,4- b] [1,3,4]thiadiazoles and 6-mercapto-3-(4-substituted phenoxy-methyl)-1,2,4-triazolo[3,4- b] [1,3,4]thiadiazoles. The anthelmintic activity of representative compounds was studied.