Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

605
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
605
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

833
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
833
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

861
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
861
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

347
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
347
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

964
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
964
Pericarditis I: Introduction01:22

Pericarditis I: Introduction

685
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
685

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functional analysis of novel genetic variants of NKX2-5 associated with nonsyndromic congenital heart disease.

American journal of medical genetics. Part A·2021
Same author

Functionally significant, novel GATA4 variants are frequently associated with Tetralogy of Fallot.

Human mutation·2018
Same author

Echocardiography in the diagnosis of apical non-compaction associated with congenital heart diseases.

Journal of echocardiography·2016
Same author

Transposition of great arteries with natural partial Senning: A rare case report.

Acute cardiac care·2016
Same author

Multiple intracardiac tumors secondary to non-Hodgkin lymphoma.

Journal of echocardiography·2015
Same author

Percutaneous device closure of patent ductus arteriosus with pulmonary artery hypertension: long-term results.

Journal of interventional cardiology·2014

Related Experiment Video

Updated: Apr 14, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

4.5K

Purulent pericarditis with quadruple valve endocarditis.

Huliyurdurga S Setty Natrajsetty1, Ishwarappa B Vijayalakshmi1, Chitra Narasimhan1

  • 1Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru, Karnataka, India.

The American Journal of Case Reports
|April 24, 2015
PubMed
Summary

Infective endocarditis (IE) affecting all four heart valves and the pericardium is rare. A child with this severe condition improved dramatically with tigecycline treatment and pericardiocentesis.

More Related Videos

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

2.8K
An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

7.4K

Related Experiment Videos

Last Updated: Apr 14, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

4.5K
Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
08:12

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

2.8K
An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
07:50

An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues

Published on: January 7, 2019

7.4K

Area of Science:

  • Pediatric Cardiology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Infective endocarditis (IE) presents with diverse clinical manifestations.
  • Pericardial involvement and IE affecting all four cardiac valves are rare, more frequently seen in intravenous drug users.
  • This case highlights an unusual presentation in a pediatric patient.

Observation:

  • A 7-year-old boy presented with purulent pericarditis and infective endocarditis involving all four cardiac valves.
  • Vegetations were observed in the left ventricle and right atrium.
  • Pericardial fluid culture identified methicillin-resistant Staphylococcus aureus (MRSA) susceptible to tigecycline.

Findings:

  • The patient received treatment with tigecycline.
  • Aggressive management included pericardiocentesis.
  • The child demonstrated a dramatic clinical improvement following treatment.

Implications:

  • Prompt diagnosis and aggressive management, including pericardiocentesis and targeted antibiotics, are crucial for favorable outcomes.
  • Tigecycline demonstrates potential as a safe and effective life-saving antibiotic in pediatric cases of severe IE.
  • This case underscores the importance of considering broad-spectrum antibiotics in complex pediatric infections.