Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Relaxation of Skeletal Muscles01:29

Relaxation of Skeletal Muscles

10.6K
The period of muscle contraction primarily influences the duration of stimulation at the neuromuscular junction (NMJ), the presence of free calcium ions in the sarcoplasm, and the availability of energy or ATP to support contractions.
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open....
10.6K
Restorative Care01:19

Restorative Care

2.5K
Restorative care is provided once a patient has been discharged from a healthcare facility and requires additional services. The additional services include home care, rehabilitation programs, and extended care. Restorative care centers help the patient regain their previous level of functioning or acquire a new level of functioning due to the incapacitating effects of a disease or a disability. It aims to assist patients in enhancing their quality of life by encouraging independence,...
2.5K
Pulse Assessment Sites01:11

Pulse Assessment Sites

3.5K
Pulse assessment sites are crucial in evaluating a patient's cardiovascular health. By assessing the pulsations of arteries at specific anatomical locations, healthcare professionals can gather valuable information about blood flow, heart rate, and peripheral circulation. Understanding these pulse assessment sites is essential for conducting comprehensive cardiovascular evaluations and monitoring patients' overall health. These sites are strategically chosen due to the accessibility and...
3.5K
Classification of Skeletal Muscle Relaxants01:28

Classification of Skeletal Muscle Relaxants

3.4K
Skeletal muscle relaxants are a group of drugs that can reduce muscle stiffness and induce temporary paralysis to relieve pain. These agents can act centrally to reduce muscle tone or spasms in painful conditions such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), or spinal injuries; they are called antispasmodics or spasmolytics.
Peripherally acting skeletal muscle relaxants interfere with the neurotransmission at the neuromuscular end plate to induce paralysis during...
3.4K
The Phragmoplast01:59

The Phragmoplast

6.7K
Cell division is essential for organismal growth and development. In animal cells, the central spindle and its associated proteins form the midbody, a structure that has an essential role in cytokinesis. In plants, the central spindle, along with the microtubules, actin, and other cell components, matures into the phragmoplast, which is necessary for cytokinesis. Unlike the stationary midbody, the phragmoplast expands centrifugally, eventually leading to the formation of the new cell wall.
The...
6.7K
The Phragmoplast01:59

The Phragmoplast

2.2K
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Potential of Digital Twins for Pediatric Rare Diseases.

CPT: pharmacometrics & systems pharmacology·2026
Same author

From FAIR to CURE: guidelines for computational models of biological systems.

NPJ systems biology and applications·2026
Same author

The 2025 Westlake Autumn Symposium for Al Proteomics and Virtual Cell.

Genomics, proteomics & bioinformatics·2026
Same author

Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS.

Cancer cell·2026
Same author

Application of Large Language Models for Annotating Genes into Reactome Pathways.

bioRxiv : the preprint server for biology·2026
Same author

IHMValidation: Assessment of Integrative Structure Models Deposited to the Protein Data Bank.

Journal of molecular biology·2025
Same journal

Correction to 'New origin firing is inhibited by APC/CCdh1 activation in S-phase after severe replication stress'.

Nucleic acids research·2026
Same journal

VeloRM: disentangling pre- and post-splicing RNA modification dynamics at single-cell resolution.

Nucleic acids research·2026
Same journal

Accessibility of telomeric overhangs to stabilizing small-molecule ligands.

Nucleic acids research·2026
Same journal

Multivalent interactions mediate SNAIL transcription factor stimulation of the nucleosome deacetylase activity of the CoREST complex.

Nucleic acids research·2026
Same journal

Genome-wide mapping of DNA G-quadruplexes in Trypanosoma brucei chromatin reveals enrichment in coding regions and transcription start sites.

Nucleic acids research·2026
Same journal

Correction to 'The Gene Ontology knowledgebase in 2026'.

Nucleic acids research·2026
See all related articles

Related Experiment Video

Updated: Apr 14, 2026

gP2S, an Information Management System for CryoEM Experiments
13:01

gP2S, an Information Management System for CryoEM Experiments

Published on: June 10, 2021

6.1K

Introducing the PRIDE Archive RESTful web services.

Florian Reisinger1, Noemi del-Toro1, Tobias Ternent1

  • 1European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.

Nucleic Acids Research
|April 24, 2015
PubMed
Summary
This summary is machine-generated.

The PRIDE database now offers new REST web services for programmatic access to mass spectrometry proteomics data. These services enable efficient retrieval and filtering of peptide, protein, and metadata from the PRIDE Archive.

More Related Videos

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

16.2K
The ITS2 Database
16:17

The ITS2 Database

Published on: March 12, 2012

32.6K

Related Experiment Videos

Last Updated: Apr 14, 2026

gP2S, an Information Management System for CryoEM Experiments
13:01

gP2S, an Information Management System for CryoEM Experiments

Published on: June 10, 2021

6.1K
Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web
09:51

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

16.2K
The ITS2 Database
16:17

The ITS2 Database

Published on: March 12, 2012

32.6K

Area of Science:

  • Proteomics
  • Bioinformatics
  • Data Science

Background:

  • The PRoteomics IDEntifications (PRIDE) database is a leading repository for mass spectrometry (MS)-based proteomics data.
  • Previous programmatic data access relied on the PRIDE BioMart interface, which faced scalability issues.

Purpose of the Study:

  • To develop new REST (REpresentational State Transfer) web services for the PRIDE Archive.
  • To provide efficient programmatic access to proteomics data, addressing limitations of the previous system.

Main Methods:

  • Development of new RESTful web services to replace the discontinued PRIDE BioMart.
  • Implementation of an Application Programming Interface (API) for querying and retrieving data.
  • Integration with the newly developed PRIDE Archive.

Main Results:

  • The new API allows programmatic querying and retrieval of peptide and protein identifications.
  • Users can access project and assay metadata, as well as original submission files.
  • Advanced searching and filtering capabilities are available based on metadata such as sample details, instrumentation, and keywords.

Conclusions:

  • The PRIDE Archive web services offer a scalable and robust solution for accessing proteomics data.
  • The API has been adopted by several bioinformatics tools and applications, enhancing data usability.
  • These services facilitate data discovery and analysis for the proteomics research community.