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Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
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Expression of nephronectin is inhibited by oncostatin M via both JAK/STAT and MAPK pathways

Tamaki Kurosawa1, Atsushi Yamada2, Masamichi Takami3

  • 1Department of Biochemistry, School of Dentistry, Showa University, Shinagawa, Tokyo 142-8555, Japan ; Division of Biological Chemistry, Department of Molecular Biology, Showa University School of Pharmacy, Shinagawa, Tokyo 142-8555, Japan.

FEBS Open Bio
|April 24, 2015
PubMed

Keywords:
BMP-2, bone morphogenetic protein-2ERK, extracellular signal-regulated kinaseJAK, janus kinaseJAK/STATJNK, c-Jun N-terminal kinaseMAM, meprin, A5 protein, and receptor protein-tyrosine phosphatase μMAPKMAPK, mitogen-activated protein kinaseMEF2, myocyte enhancer-binding factor 2ANephronectinNpnt, nephronectinOSM, oncostatin MOSMR, OSM receptorOncostatin MSTAT, signal transducer and activator of transcriptionTGF-β, transforming growth factor-βTNF-α, tumor necrosis factor-α

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