Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Natural noncoding <i>pumilio</i> variants retune value-coding interneurons to bias <i>Drosophila</i> oviposition decisions.

Science advances·2026
Same author

IMK2-IMK3 module regulates biogenesis of nascent cell walls and postcytokinetic differentiation in <i>Arabidopsis thaliana</i>.

Science advances·2026
Same author

A legal epidemiology analysis of state civil provisions addressing non-consensual condom removal (stealthing) in the United States.

Journal of public health policy·2026
Same author

Natural non-coding <i>pumilio</i> variants retune value-coding interneurons to bias <i>Drosophila</i> oviposition choices.

bioRxiv : the preprint server for biology·2025
Same author

Genotype-Specific Activation of Autophagy during Heat Wave in Wheat.

Cells·2024
Same author

A lightweight data-driven spiking neuronal network model of <i>Drosophila</i> olfactory nervous system with dedicated hardware support.

Frontiers in neuroscience·2024

Related Experiment Video

Updated: Apr 14, 2026

Operant Learning of Drosophila at the Torque Meter
17:31

Operant Learning of Drosophila at the Torque Meter

Published on: June 16, 2008

14.1K

Learning: the good, the bad, and the fly.

Toshihide Hige1, Glenn Turner1

  • 1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

Neuron
|April 24, 2015
PubMed
Summary
This summary is machine-generated.

Scientists explored how the fruit fly brain forms pleasant or unpleasant smell memories. This research uncovers key neural circuits involved in olfactory learning and memory, providing insights into how we perceive scents.

More Related Videos

In Vivo Optical Calcium Imaging of Learning-Induced Synaptic Plasticity in Drosophila melanogaster
06:35

In Vivo Optical Calcium Imaging of Learning-Induced Synaptic Plasticity in Drosophila melanogaster

Published on: October 8, 2019

9.9K
An Improved Method for Accurate and Rapid Measurement of Flight Performance in Drosophila
06:18

An Improved Method for Accurate and Rapid Measurement of Flight Performance in Drosophila

Published on: February 13, 2014

12.8K

Related Experiment Videos

Last Updated: Apr 14, 2026

Operant Learning of Drosophila at the Torque Meter
17:31

Operant Learning of Drosophila at the Torque Meter

Published on: June 16, 2008

14.1K
In Vivo Optical Calcium Imaging of Learning-Induced Synaptic Plasticity in Drosophila melanogaster
06:35

In Vivo Optical Calcium Imaging of Learning-Induced Synaptic Plasticity in Drosophila melanogaster

Published on: October 8, 2019

9.9K
An Improved Method for Accurate and Rapid Measurement of Flight Performance in Drosophila
06:18

An Improved Method for Accurate and Rapid Measurement of Flight Performance in Drosophila

Published on: February 13, 2014

12.8K

Area of Science:

  • Neuroscience
  • Olfactory system research
  • Animal behavior

Background:

  • Olfactory memories significantly influence behavior and perception.
  • The neural basis for pleasant versus repulsive odor associations remains largely unknown.
  • Understanding odor perception is crucial for various fields, including neuroscience and psychology.

Purpose of the Study:

  • To investigate the neural mechanisms underlying the formation of olfactory memories in Drosophila.
  • To identify specific brain regions and circuits responsible for differentiating between positive and negative odor associations.
  • To elucidate how the fly brain processes and stores scent-related information.

Main Methods:

  • Utilized advanced genetic and imaging techniques in Drosophila melanogaster.
  • Mapped neural activity in deep brain areas associated with olfactory processing.
  • Performed behavioral experiments to assess odor-guided learning and memory.

Main Results:

  • Identified specific neuronal populations in the Drosophila brain involved in olfactory memory.
  • Demonstrated that distinct circuits mediate the association of odors with positive or negative outcomes.
  • Provided evidence for the role of specific signaling pathways in olfactory learning.

Conclusions:

  • The study reveals fundamental principles of olfactory memory formation in a model organism.
  • Findings offer insights into the neural computations that shape our perception of smells.
  • This research lays the groundwork for future studies on the neurobiology of memory and emotion.