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Related Experiment Video

Updated: Apr 14, 2026

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

Published on: March 8, 2013

MR lymphangiography: How i do it.

Lee M Mitsumori¹, Elizabeth S McDonald², Gregory J Wilson³

¹Department of Radiology, Straub Clinic and Hospital, Honolulu, Hawaii, USA.

Journal of Magnetic Resonance Imaging : JMRI

|April 25, 2015

Summary

This summary is machine-generated.

Magnetic resonance imaging (MRI) offers a new way to diagnose lymphedema and map lymphatic channels for microsurgery. This high-resolution dynamic 3D MRI technique aids in surgical planning for lymphaticovenular anastomosis.

Keywords:

MR lymphangiography breast cancer image postprocessing lymphaticovenular anastomosis lymphedema microsurgery

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A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice

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A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice

A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice

Published on: November 2, 2019

Area of Science:

Medical Imaging
Microsurgery
Vascular Surgery

Background:

Lymphedema is a chronic condition often caused by cancer treatment.
Current imaging like lymphoscintigraphy lacks surgical planning detail.
Microsurgical lymphaticovenular anastomosis requires precise lymphatic channel mapping.

Purpose of the Study:

To evaluate high-resolution dynamic 3D MRI for diagnosing lymphedema.
To assess MRI's utility in mapping lymphatic channels for microsurgery.
To detail an MRI protocol for lymphedema assessment and surgical planning.

Main Methods:

Utilized 1.5T or 3.0T MRI with multichannel phased array coils.
Employed heavily T2-weighted 3D sequences for edema assessment.
Performed dynamic 3D gradient echo imaging post-intracutaneous contrast for lymphatic visualization.
Used delayed 3D gradient echo sequences post-intravenous contrast for venous mapping.

Main Results:

High-resolution dynamic 3D MRI can noninvasively diagnose lymphedema.
MRI effectively depicts the location and number of abnormal lymphatic channels.
The described MRI protocol provides detailed spatial information for surgical planning.

Conclusions:

High-resolution dynamic 3D MRI is a valuable tool for lymphedema diagnosis.
MR lymphangiography facilitates presurgical planning for lymphaticovenular anastomosis.
MRI enhances the precision of microsurgical treatment for lymphedema.