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Updated: Apr 14, 2026

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy
Published on: October 24, 2017
A model of vesicle tubulation and pearling induced by adsorbing particles
1Department of Physics and Astronomy, University of Waterloo, Waterloo, Ontario, CanadaN2L 3G1. jeffchen@uwaterloo.ca.
Abstract:
We study the basic theoretical model of a deformable vesicle immersed in a solution of particles that can adsorb onto one of the two surfaces of a membrane. The model consists of an adsorption energy gain for the adsorbing particles and the Canham-Helfrich membrane bending energy, in which the spontaneous curvature is coupled with the adsorption area. We demonstrate that bud, pearling, and tube conformations can be stabilized after minimizing the free energy and that the pearling-tubulation transition has the characteristics of an abrupt structural transition.
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