Related Experiment Video

Updated: Apr 14, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

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Benzothiazepine CGP37157 and its 2'-isopropyl analogue modulate Ca²⁺ entry through CALHM1

Ana J Moreno-Ortega1, Francisco J Martínez-Sanz2, Rocío Lajarín-Cuesta2

  • 1Instituto Teófilo Hernando, Departamento de Farmacología y Terapéutica, Universidad Autónoma de Madrid, C/ Arzobispo Morcillo, 4, 28029, Madrid, Spain; Servicio de Farmacología Clínica, Instituto de Investigación Sanitaria, Hospital Universitario de la Princesa, C/ Diego de León, 62, 28006, Madrid, Spain.

Neuropharmacology
|April 25, 2015
PubMed

Keywords:
BenzothiazepinesCGP37157Calcium homeostasis modulator 1 (CALHM1)Carbonyl cyanide-p-trifluoromethoxyphenylhydrazoneDimebolinFCCPITH12575Neurodegenerative diseasesPubChem CID: 197033PubChem CID: 2688PubChem CID: 3330

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