Related Experiment Video
Updated: Apr 14, 2026

Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension
Published on: November 15, 2024
A rare cause of gastrointestinal bleeding, "GANT"
Fuat İpekçi1, Ömer Engin, Yahya Çapkis
1Department of Surgery, Tepecik Training and Research Hospital, İzmir, Turkey. fuipek@hotmail.com.
Insights
Gastrointestinal stromal tumors (GISTs), a rare mesenchymal tumor, can cause acute gastrointestinal bleeding. This case report highlights a GIST as a potential cause of emergency surgical bleeding.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- Acute gastrointestinal hemorrhage is a common surgical emergency.
- Benign pathologies typically cause acute gastrointestinal bleeding.
- Gastrointestinal tumors, though rare, must be considered in the differential diagnosis.
Observation:
- This case report details a patient presenting with acute gastrointestinal hemorrhage.
- The patient was diagnosed with a gastrointestinal autonomic nerve tumor (GANT).
- GANTs are rare mesenchymal tumors originating from Cajal cells or their precursors.
Findings:
- Gastrointestinal autonomic nerve tumors (GANTs) are exceptionally rare.
- Cajal cells function as pacemaker cells within the intestinal wall.
- This case underscores the potential for GANTs to manifest as acute gastrointestinal bleeding.
Implications:
- Reporting rare GANT cases contributes to understanding the etiology of acute gastrointestinal hemorrhage.
- Such cases may offer new perspectives on the diagnosis and management of rare gastrointestinal tumors.
- Further research into rare mesenchymal tumors is warranted to improve diagnostic and therapeutic strategies.
Abstract:
Acute gastrointestinal hemorrhage is frequently seen in emergency surgical conditions. Benign pathologies are generally responsible in etiologic factors. Our case is a GANT. GANT is a mesenchymal tumor originated from Cajal cells or precursors of them. Cajal cells are pacemaker cells in the intestinal wall. Because GANT is a very rare tumor, we would like to report our case to the medical literature. We think very rare cases and treatments of its as like our case create view point states in etiology of acute gastrointestinal hemorrhage.
Related Concept Videos
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Esophageal Varices-I: Introduction
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Disorders of Hemostasis
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Other Disorders of Digestive System
