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Effect of long-term pulsed electromagnetic field exposure on hepatic and immunologic functions of rats
Bao-lin Li1, Wei Li1, Jia-Qi Bi1
1Department of Orthopaedic Surgery, The First Hospital of Harbin City, Harbin Medical University, No. 149, Mai Mai Street, Dao Li District, 150001, Harbin, Heilongjiang Province, China.
Background:
In this report, the effects of long-term pulsed electromagnetic field (PEMF) exposure on hepatic and immunologic functions were examined.
Methods:
Male rats were randomly divided into four groups: a control group and three experimental groups exposed to a 50-Hz PEMF at 5, 10, or 20 mT for 10 weeks.
Results:
Compared with the control group, activities of serum alanine aminotransferase and aspartate aminotransferase and concentrations of serum, liver, and spleen Metabolism of lipid peroxidation (MDA) in the 10- and 20-mT PEMF groups were significantly increased. The activities of Glutathione peroxidase (GSH-Px) and Superoxide Dismutase (SOD) in the serum, liver, and spleen and concentrations of serum immunoglobulins were significantly decreased.
Conclusion:
These results demonstrate that long-term exposure to PEMF can lead to oxidative damage of the liver and spleen.
