Related Experiment Video
Updated: Apr 14, 2026

Author Spotlight: Identifying Compensatory Pathways in Malaria Parasites Containing Hypomorphic Allele of Essential Protein Kinases
Published on: November 22, 2024
How genomics is contributing to the fight against artemisinin-resistant malaria parasites
Pedro Cravo1, Hamilton Napolitano2, Richard Culleton3
1Laboratory of Genomics and Biotechnology (GenoBio), IPTSP, Universidade Federal de Goiás, Goiânia 74605050, GO, Brazil; PPSTMA, Centro Universitário de Anápolis (UniEVANGÉLICA), Anápolis 75083515, GO, Brazil; Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon 1349-008, Portugal.
Abstract:
Plasmodium falciparum, the malignant malaria parasite, has developed resistance to artemisinin, the most important and widely used antimalarial drug at present. Currently confined to Southeast Asia, the spread of resistant parasites to Africa would constitute a public health catastrophe. In this review we highlight the recent contributions of genomics to our understanding how the parasite develops resistance to artemisinin and its derivatives, and how resistant parasites may be monitored and tracked in real-time, using molecular approaches.
More Related Videos
10:27Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria
Published on: November 10, 2015
15:03Building a Better Mosquito: Identifying the Genes Enabling Malaria and Dengue Fever Resistance in A. gambiae and A. aegypti Mosquitoes
Published on: July 4, 2007
Related Concept Videos
Pharmacogenomics: Identification of New Drug Targets
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Pharmacogenetics and Pharmacogenomics: Overview
Genomics