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Antimicrobial agents from selected medicinal plants in Libya.

Hasan M H Muhaisen1, Miftah Mailoud Ab-Mous2, Fadel A Ddeeb2

  • 1Faculty of Science and Arts, Sharora, University of Najran, Najran, Saudi Arabia.

Chinese Journal of Integrative Medicine
|April 26, 2015
PubMed
Summary

Methanolic extracts from five Libyan folk medicinal plants demonstrated significant in vitro antibacterial activity against Gram-positive and Gram-negative bacteria. These findings support the traditional use of these plants in treating infections.

Keywords:
Libyan folk medicineantimicrobial activitymedicinal plant extractsminimum inhibitory concentration

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Area of Science:

  • Pharmacology
  • Ethnobotany
  • Microbiology

Background:

  • Libyan folk medicine extensively utilizes various plant species for treating ailments.
  • Scientific validation of these traditional remedies is crucial for understanding their therapeutic potential.

Purpose of the Study:

  • To evaluate the in vitro antimicrobial efficacy of water and methanol extracts from 23 Libyan folk medicinal plants.
  • To identify specific plant species with significant antibacterial properties.

Main Methods:

  • The well-diffusion method was employed to assess antimicrobial activity against four reference microorganisms: Escherichia coli, Salmonella species, Staphylococcus aureus, and Bacillus subtilis.
  • Minimum Inhibitory Concentration (MIC) was determined for potent extracts.

Main Results:

  • Five methanolic extracts (Rosmarinus officinalis, Carduus marianium, Lantana camara, Rhus tripartite, and Thymus capitatus) exhibited notable antimicrobial activity against Staphylococcus aureus, Bacillus subtilis, and Salmonella species.
  • MIC values ranged from 1.25 mg/mL for Thymus capitatus to 5 mg/mL for Rosmarinus officinalis and Lantana camara.

Conclusions:

  • Crude methanolic extracts of selected Libyan folk medicinal plants possess mild to high in vitro antibacterial activities.
  • The study provides scientific evidence supporting the traditional use of these plants in combating bacterial infections.