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Related Concept Videos

Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Related Experiment Video

Updated: Apr 14, 2026

In Vivo Quantification of Hip Arthrokinematics during Dynamic Weight-bearing Activities using Dual Fluoroscopy
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Excess mortality associated with second hip fracture.

B Sobolev1, K J Sheehan, L Kuramoto

  • 1School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada, boris.sobolev@ubc.ca.

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
|April 26, 2015
PubMed
Summary
This summary is machine-generated.

A second hip fracture significantly increases the risk of death, beyond age-related mortality. Implementing secondary prevention strategies after a hip fracture could save lives.

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Area of Science:

  • Gerontology
  • Orthopedics
  • Public Health

Background:

  • Hip fractures are a significant cause of mortality.
  • Approximately 10% of hip fracture survivors experience a second hip fracture.
  • The impact of a second hip fracture on mortality risk is not well-established.

Purpose of the Study:

  • To investigate whether a second hip fracture is associated with an increased risk of death.
  • To determine if this increased mortality risk is independent of age.

Main Methods:

  • Retrospective analysis of 42,435 hospitalization records.
  • Inclusion criteria: patients aged 60 years or older, discharged after hip fracture surgery (1990-2005).
  • Outcome measured: time to death.

Main Results:

  • The monthly death rate was higher for patients with a second hip fracture (21.1/1000 patient-months) compared to those without (16.2/1000 patient-months).
  • Second hip fracture increased the hazard of death by 55% (Hazard Ratio [HR] = 1.55, 95% CI 1.47-1.63).
  • This increased risk was observed in both men (HR=1.58) and women (HR=1.54) and was not statistically different between sexes.

Conclusions:

  • Second hip fracture elevates the risk of death beyond age-related increases for both men and women.
  • Findings highlight the critical need for effective secondary prevention strategies post-hip fracture.
  • Implementing such strategies has the potential to reduce morbidity and mortality.