Related Experiment Video
Updated: Apr 14, 2026

Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Olfactory and Gustatory Function After Bariatric Surgery
Franca Holinski1, Charalambos Menenakos2, Georg Haber2
1Department of Otorhinolaryngology, Head, and Neck Surgery, Charité, University Medicine Berlin, Charité Campus Mitte, Charitéplatz 1, 10117, Berlin, Germany. franca.holinski@charite.de.
Background:
Neither hormone levels nor malabsorption alone fully explains the distinct weight loss after bariatric surgery in morbidly obese patients. Postoperatively, patients regularly report a change in the sense of taste and the development of food aversions. Hedonic and sensory components like olfactory and gustatory stimuli significantly affect appetite and flavour.
Methods:
We prospectively analysed the orthonasal olfactory and gustatory function with psychophysical testing in 44 patients undergoing laparoscopic Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG) or adjustable gastric banding (AGB) and in 23 healthy controls.
Results:
About 22.7 % of morbidly obese patients were hyposmic, showing significantly lower threshold-discrimination-identification (TDI) scores (p = 0.009) with decreased discrimination and identification ability. In addition, 22.7 % of patients were tested to be limited in gustatory function, with significantly lower taste strip test (TST) scores (p = 0.003). Six months after surgery, olfactory and gustatory function was not different when compared to healthy controls.
Conclusions:
Due to obesity, patients frequently show impaired olfactory and gustatory function. Six months after laparoscopic bariatric surgery, both chemosensory functions improve. The TDI test is an appropriate tool to measure olfactory function in obese patients.
Related Concept Videos
Olfactory Receptors: Location and Structure
Taste Buds and Receptors
The Physiology of Taste
Gustation
Physiology of Smell and Olfactory Pathway
The olfactory...
Olfaction
The olfactory receptors are embedded in the cilia of the...

