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Transfusion of ABO-incompatible platelets causing severe haemolytic reaction

M D Reis1, A S Coovadia

  • 1Department of Laboratory Haematology, Sunnybrook Medical Centre, Toronto, Ontario, Canada.

Not infrequently clinical demand dictates that patients receive transfusions of ABO-incompatible platelets when there is a short supply of group-specific platelets. This carries a risk of causing a haemolytic reaction, as illustrated in the clinical case we report. In discussing this potential complication, we suggest a strategy for avoiding it.

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