Related Experiment Video
Updated: Apr 14, 2026

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
Published on: March 17, 2023
Retrograde approach via left internal mammary artery using a 5 Fr guiding catheter
Sho Torii1, Naoki Masuda2, Yuji Ikari2
1Department of Cardiology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. shoz3333@gmail.com.
Insights
A novel retrograde approach successfully treated a blocked saphenous vein graft (SVG) in the right coronary artery (RCA) causing myocardial infarction. This technique avoided complications associated with direct intervention on the diseased SVG.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Vascular Surgery
Background:
- Coronary artery bypass grafting (CABG) is a common procedure for coronary artery disease.
- Saphenous vein grafts (SVGs) are frequently used but prone to degeneration and occlusion.
- Non-ST elevation myocardial infarction (NSTEMI) with acute heart failure presents complex management challenges, especially with prior CABG.
Observation:
- A 64-year-old female with prior CABG presented with NSTEMI and acute heart failure.
- The SVG-RCA was identified as the culprit lesion due to angiographic thrombus.
- Direct percutaneous coronary intervention (PCI) of the SVG-RCA posed a high risk of distal embolization and slow-flow phenomenon.
Findings:
- A successful primary PCI was achieved using a retrograde approach to the native right coronary artery (RCA).
- The retrograde access utilized a septal channel originating from the left anterior descending artery, bypassed by a left internal mammary artery (LIMA) graft.
- A microcatheter and guidewire were navigated through the LIMA and septal collateral to reach the distal native RCA.
Implications:
- This case demonstrates the feasibility and success of a retrograde PCI approach for complex SVG interventions.
- The technique offers a viable alternative when direct antegrade intervention carries significant embolic risk.
- This strategy may improve outcomes for patients with degenerated vein grafts presenting with acute coronary syndromes.
Abstract:
A 64-year-old female, who had undergone CABG previously, was admitted to our hospital because of non-ST elevation myocardial infarction with acute heart failure. The SVG-RCA was judged the culprit vessel because of the angiographical thrombus. However, primary percutaneous coronary intervention (PCI) in the SVG-RCA had a high risk of distal embolism and might have had caused critical slow flow. Primary PCI to the native right coronary artery (RCA) with retrograde approach using the septal channel from left anterior descending artery bypassed by LIMA was successfully performed. A 5 Fr JR-4.0 guiding catheter was deeply engaged to the mid part of LIMA following the microcatheter, and the wire finally reached the distal part of RCA.
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