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Published on: November 15, 2017
Miniaturization of a micro-optics array for highly sensitive and parallel detection on an injection moulded
Tran Quang Hung1, Yi Sun, Carl Esben Poulsen
1DTU Nanotech, Department of Micro- and Nanotechnology, Technical University of Denmark, Ørsteds Plads, DK-2800 Kgs. Lyngby, Denmark. anders.wolff@nanotech.dtu.dk.
Abstract:
A miniaturised array of supercritical angle fluorescence (SAF) micro-optics embedded in a microfluidic chamber was fabricated by injection moulding. The fabricated chip could enhance the fluorescence signal around 46 times compared to a conventional microscope. Collection of the fluorescence signal from the SAF array is almost independent of the numerical aperture, and the limit of detection was improved 36-fold using a simple and inexpensive optical detection system.
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