Related Experiment Video

Updated: Aug 15, 2026

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
07:29

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein

Published on: October 12, 2017

Cardiolipin antibody levels in endometriosis and systemic lupus erythematosus

S H Kennedy1, B Nunn, S A Cederholm-Williams

  • 1Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Headington, Oxford, United Kingdom.

Fertility and Sterility
|December 1, 1989
PubMed

Insights

Cardiolipin antibody levels are higher in women with endometriosis and Systemic Lupus Erythematosus (SLE) compared to healthy individuals. This finding suggests a potential link between these conditions and autoimmune markers.

Area of Science:

  • Immunology
  • Gynecology
  • Rheumatology

Background:

  • Cardiolipin antibodies are associated with autoimmune diseases.
  • Endometriosis and Systemic Lupus Erythematosus (SLE) are chronic inflammatory conditions.
  • The role of cardiolipin antibodies in endometriosis requires further investigation.

Purpose of the Study:

  • To investigate cardiolipin antibody levels in women with endometriosis.
  • To compare cardiolipin antibody levels between women with endometriosis, SLE, and healthy controls.

Main Methods:

  • Measurement of cardiolipin antibody levels using serological assays.
  • Comparative analysis of antibody levels across study groups.

Main Results:

  • Significantly elevated cardiolipin antibody levels were observed in women with endometriosis compared to healthy women.
  • Women with SLE also exhibited significantly higher cardiolipin antibody levels than healthy women.
  • Cardiolipin antibody levels were comparable between women with endometriosis and SLE.

Conclusions:

  • Elevated cardiolipin antibody levels are associated with endometriosis.
  • Cardiolipin antibodies may serve as a potential biomarker in endometriosis.
  • Further research is warranted to elucidate the pathogenic role of cardiolipin antibodies in endometriosis.

More Related Videos

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice09:43

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice

Published on: June 8, 2022

Platform for Quantitative Detection of Endometrial Immune Cells Based on Immunohistochemistry and Digital Image Analysis07:46

Platform for Quantitative Detection of Endometrial Immune Cells Based on Immunohistochemistry and Digital Image Analysis

Published on: October 13, 2023

Related Concept Videos

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...