Related Experiment Video
Updated: Apr 14, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Acute Mesenteric Ischemia Is a More Common Cause than Expected of Acute Abdomen in the Elderly
Jussi M Kärkkäinen1, Tiina T Lehtimäki, Hannu Manninen
1Heart Center, Kuopio University Hospital, PL 100, Kuopio, 70029, KYS, Finland, jkarkkai@gmail.com.
Background:
The incidence of acute mesenteric ischemia (AMI) increases exponentially with age. The significance of AMI as a differential diagnosis in elderly patients with acute abdomen may be underestimated.
Methods:
Consecutive patients hospitalized for AMI between 2009 and 2013 were retrospectively identified in a well-defined population. Acute appendicitis, ruptured abdominal aortic aneurysm, acute pancreatitis, and acute cholecystitis were used as reference diagnoses, and the age-specific incidence rates were calculated. In addition, long-term mortality risk was assessed for AMI survivors.
Results:
The in-hospital incidence rates of AMI, acute obstructive mesenteric ischemia, and non-obstructive mesenteric ischemia were 7.3, 4.5, and 2.0/100,000/year, respectively. AMI was more common than ruptured abdominal aortic aneurysm, and the age-specific incidence of AMI was higher than the incidence of acute appendicitis in patients over age 75 years with acute abdomen. During the follow-up, the age-adjusted risk of death was 1.8 times higher in AMI survivors than in survivors of acute cholecystitis.
Conclusion:
AMI may be a more common cause of acute abdomen in elderly patients than is generally thought, emphasizing the importance of performing urgent computed tomography with contrast enhancement preferably in arterial and venous phases in these patients.
Insights
Acute mesenteric ischemia (AMI) is more common in older adults than previously thought. Early diagnosis with CT scans is crucial for better outcomes in elderly patients with acute abdomen.
Area of Science:
- Gastroenterology
- Vascular Surgery
- Geriatrics
Background:
- Acute mesenteric ischemia (AMI) incidence rises sharply with age.
- AMI's role in elderly acute abdomen cases may be underestimated.
Purpose of the Study:
- To determine the incidence of AMI in an elderly population.
- To compare AMI incidence with other acute abdominal conditions.
- To assess long-term mortality in AMI survivors.
Main Methods:
- Retrospective analysis of hospitalized AMI patients (2009-2013).
- Calculation of age-specific incidence rates for AMI and reference diagnoses.
- Assessment of long-term mortality risk for AMI survivors.
Main Results:
- In-hospital AMI incidence: 7.3/100,000/year.
- AMI incidence exceeds ruptured abdominal aortic aneurysm.
- AMI incidence is higher than appendicitis in patients >75 years.
- AMI survivors face 1.8x higher mortality risk than acute cholecystitis survivors.
Conclusions:
- AMI is a significant cause of acute abdomen in the elderly.
- Urgent contrast-enhanced CT is vital for diagnosing AMI in this demographic.
More Related Videos
07:05Visualization of Neutrophil Extracellular Traps in Mesenteric Venules After Mesenteric Ischemia-Reperfusion Injury via Intravital Microscopy
Published on: September 27, 2024
04:57Author Spotlight: Advancing Spectral Characterization of Physiological and Malperfused Tissues
Published on: July 5, 2024
Related Concept Videos
Acute Pancreatitis II: Clinical Manifestations and Management
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Peptic Ulcer