Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

10.5K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
10.5K
Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

2.1K
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
2.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Denoising of low-dose chest computed tomography images using a U-net based convolutional autoencoder and transfer learning.

Biomedical physics & engineering express·2026
Same author

Brain Age in Conduct Disorder:: A Mega-Analysis of the ENIGMA Antisocial Behavior Working Group.

bioRxiv : the preprint server for biology·2026
Same author

Toward Harmonizing Quantification of Dopamine Neuron Imaging Biomarkers in Parkinson's Disease: The Centamine Scale.

Annals of neurology·2026
Same author

Underreporting of Coronary Stents in LDCT for Lung Cancer Screening and Their Differentiation From Severe Coronary Artery Calcifications.

Journal of computer assisted tomography·2026
Same author

Correction: CCM-ITALUNG2 pilot on lung cancer screening in Italy: recruitment, integration with smoking cessation and baseline results.

La Radiologia medica·2025
Same author

Central Nervous System Biodistribution and Pharmacokinetics of Radiolabeled Tofersen in Rodents, Nonhuman Primates, and Humans.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine·2025
Same journal

Systematic comparison of MPRAGE and BRAVO T1-weighted MRI pulse sequences and brain morphometry in high-risk young adults.

Magnetic resonance imaging·2026
Same journal

Foot dynamic contrast-enhanced MRI for assessing microcirculatory changes after endovascular therapy in peripheral artery disease: A prospective pilot study.

Magnetic resonance imaging·2026
Same journal

Reconstruction of MRI from undersampled k-spaces of double-contrast volume acquisitions using deep neural networks.

Magnetic resonance imaging·2026
Same journal

Radiofrequency-induced heating safety of brain MRI scans at 7 T in the presence of a shoulder implant.

Magnetic resonance imaging·2026
Same journal

Incremental diagnostic value of microstructural time-dependent diffusion MRI in differentiating PCNSL from glioblastoma over conventional MRI.

Magnetic resonance imaging·2026
Same journal

Enhanced respiratory motion compensation in free-breathing dynamic contrast-enhanced MRI with GROG-facilitated bunch phase encoding and Golden angle radial sampling.

Magnetic resonance imaging·2026
See all related articles

Related Experiment Video

Updated: Apr 14, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

29.5K

Diffusion-MRI in neurodegenerative disorders.

Joseph Goveas1, Laurence O'Dwyer2, Mario Mascalchi3

  • 1Department of Psychiatry and Behavioral Medicine, and Institute for Health and Society, Medical College of Wisconsin, Milwaukee, WI, USA.

Magnetic Resonance Imaging
|April 29, 2015
PubMed
Summary
This summary is machine-generated.

Diffusion Magnetic Resonance Imaging (dMRI) offers sensitive brain imaging for detecting neurodegenerative diseases. This review explores dMRI

Keywords:
Alzheimer’s diseaseAmyotrophic lateral sclerosisDegenerative ataxiasDiffusion-MRIHuntington’s diseaseParkinson’s disease

More Related Videos

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

26.1K
Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
10:33

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

Published on: August 14, 2019

9.1K

Related Experiment Videos

Last Updated: Apr 14, 2026

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

29.5K
Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

26.1K
Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
10:33

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury

Published on: August 14, 2019

9.1K

Area of Science:

  • Neuroimaging
  • Radiology
  • Neurology

Background:

  • Brain abnormalities in diseases are increasingly understood through advanced imaging techniques.
  • Diffusion Magnetic Resonance Imaging (dMRI) utilizes water molecule displacement as a sensitive contrast mechanism.
  • dMRI provides detailed structural information valuable in clinical and research settings.

Purpose of the Study:

  • To review the applications, findings, and challenges of dMRI in neurodegenerative disorders.
  • To explore the potential of dMRI as an imaging biomarker for early disease detection and monitoring.
  • To summarize current research and future directions for dMRI in understanding neurodegeneration.

Main Methods:

  • Review of existing literature on diffusion-MRI applications in neurodegenerative diseases.
  • Analysis of dMRI's role in characterizing microstructural changes and neurophysiological mechanisms.
  • Exploration of dMRI's utility as a quantitative imaging biomarker.

Main Results:

  • dMRI has demonstrated utility in understanding microstructural changes in various neurodegenerative conditions.
  • Quantitative indices from dMRI can serve as potential imaging biomarkers for early detection and tracking of disease progression.
  • The technique offers insights into the neurophysiological mechanisms underlying disorders like Alzheimer's, Parkinson's, and ALS.

Conclusions:

  • Diffusion-MRI is a powerful tool for investigating neurodegenerative disorders.
  • Its quantitative nature supports its use as an imaging biomarker for early detection and patient monitoring.
  • Further research is needed to fully leverage dMRI's potential in clinical trials and patient management.