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Imaging and Quantifying Mitochondrial Morphology in C. elegans During Aging
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Mitochondrial dynamics: Orchestrating the journey to advanced age

Agnieszka K Biala1, Rimpy Dhingra1, Lorrie A Kirshenbaum1

  • 1The Institute of Cardiovascular Sciences, St. Boniface Hospital Research Centre, Winnipeg, Manitoba R2H 2A6, Canada; Department of Physiology, Faculty of Health Sciences, College of Medicine, University of Manitoba, Winnipeg, Manitoba R2H 2A6, Canada; Faculty of Health Sciences, College of Medicine, University of Manitoba, Winnipeg, Manitoba R2H 2A6, Canada.

Journal of Molecular and Cellular Cardiology
|April 29, 2015
PubMed
Summary

Aging impairs cardiac function by affecting mitochondria, the cell powerhouses. This review explores how mitochondrial aging and senescence impact cardiovascular health and heart failure risk.

Keywords:
AgingCell deathMitochondrial dynamicsOxidative stressROS

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