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A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.
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NMR spectrometers consist of a strong magnet, a radiofrequency transmitter, and a detector attached to a computer console for recording spectra of samples containing NMR-active nuclei. In first-generation NMR instruments called continuous-wave spectrometers, the resonance frequencies of the nuclei are determined by frequency-sweep or field-sweep methods. The magnetic field strength is fixed and the rf signal is swept in the former, while the radiofrequency signal is fixed and the magnetic field...
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An ultra-low cost NMR device with arbitrary pulse programming.

Hsueh-Ying Chen1, Yaewon Kim1, Pulak Nath2

  • 1Chemistry Department, Texas A&M University, College Station, TX 77845-3255, USA.

Journal of Magnetic Resonance (San Diego, Calif. : 1997)
|April 29, 2015
PubMed
Summary
This summary is machine-generated.

We developed a low-cost Nuclear Magnetic Resonance (NMR) spectrometer using readily available electronics boards, minimizing custom components. This flexible NMR system enables diverse experiments and applications with precise digital control.

Keywords:
NMR hardwarePortable NMRRelaxometry

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Area of Science:

  • Physical Sciences
  • Chemistry
  • Engineering

Background:

  • General-purpose electronics boards with microprocessors or Field Programmable Gate Arrays (FPGAs) are increasingly capable.
  • These boards offer potential for implementing Nuclear Magnetic Resonance (NMR) spectrometers with reduced custom electronics.

Purpose of the Study:

  • To demonstrate the feasibility of building an NMR spectrometer using ultra-low-cost, general-purpose electronics boards.
  • To showcase the flexibility and precision offered by FPGA technology in NMR pulse programming and frequency generation.

Main Methods:

  • Implementation of an NMR spectrometer utilizing a Field Programmable Gate Array (FPGA) board.
  • Programming of arbitrarily timed pulse sequences and digital frequency generation via FPGA.
  • Acquisition of data using a 0.53T permanent magnet, including spin-lattice relaxation and Carr-Purcell-Meiboom-Gill experiments.

Main Results:

  • Successful demonstration of a functional NMR spectrometer with minimal custom electronics.
  • Precise digital control over pulse sequences and frequencies achieved using FPGA.
  • Demonstration of diverse NMR experiments, including relaxation measurements and phase-cycled experiments for quadrature detection.

Conclusions:

  • Ultra-low-cost electronics boards are suitable for constructing versatile NMR spectrometers.
  • FPGA technology provides precise timing and flexibility for advanced NMR pulse programming.
  • This adaptable NMR spectrometer design can be tailored for various applications like relaxometry, polarimetry, and magnetometry.