Fat grafting in primary cleft lip repair
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Published on: December 5, 2025
Elizabeth Gordon Zellner1, Miles J Pfaff, Derek M Steinbacher
1New Haven, Conn. From Plastic and Reconstructive Surgery, Yale University School of Medicine.
Unlabelled:
The goal of primary cleft lip repair is to unify the lip elements and achieve a nearly normal appearance. Many techniques can confer satisfactory results; however, scarring and contour irregularities may persist. Lipofilling can modulate scar formation and enable soft-tissue augmentation. The authors hypothesize that fat grafting during immediate cleft lip repair may be of benefit. Patients who underwent primary cleft lip repair with and without immediate fat grafting were compared. Postoperative photographs were analyzed by three blinded reviewers. Cronbach statistics and a two-tailed t-test were used. Scar analysis revealed statistically significant (p < 0.05) improvement in scar appearance and contour of the fat-grafted cleft lip repair. Immediate fat grafting may be a promising strategy to improve lip appearance, contour, and scarring during primary cleft lip repair.
Clinical Question/Level Of Evidence:
Therapeutic, III.
