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Updated: Aug 10, 2026

Isolation of Leukocytes from the Human Maternal-fetal Interface
Published on: May 21, 2015
S-100 protein in glands within decidua and cervical glands during early pregnancy
Y Nakamura1, Y Moritsuka, Y Ohta
1Department of Pathology, St Mary's Hospital, Kurume, Japan.
Abstract:
Strong immunoreactivity with polyclonal S-100 protein antisera and monoclonal S-100 alpha subunit antiserum was found in glandular cells of the decidua basalis and cervical polyps during early pregnancy. Immunoreactive S-100 protein was negative in glandular cells of the endometrium and cervix of nonpregnant women. It was also negative in endometrial hyperplasia and endometrial carcinoma. While the function of S-100 protein is not known, a relationship between humoral factors related to pregnancy and expression of S-100 protein gene is suggested by the results of this study.
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