Related Experiment Video
Updated: Apr 14, 2026
10:29
Christopher Hughes: An in vitro model for the Study of Angiogenesis Interview
Published on: April 28, 2007
9.0K
[Hughes-Stovin Syndrome, a case report]
Sonia Pankl1, Ana Meraldi, Paola Pegoraro
1Servicio de Clínica Médica, Hospital Británico de Buenos Aires, Argentina.
Medicina
|April 29, 2015
Summary
Hughes-Stovin syndrome, a rare condition causing deep vein thrombosis and pulmonary artery aneurysms, can be effectively treated. High-dose corticosteroids and cyclophosphamide led to complete symptom and aneurysm regression in a patient.
Area of Science:
- Vascular Medicine
- Rare Diseases
- Immunology
Background:
- Hughes-Stovin syndrome is a rare, often fatal condition involving deep vein thrombosis and pulmonary artery aneurysms.
- Its etiology and pathogenesis remain largely unknown, with some linking it to Behcet's disease.
Observation:
- A 41-year-old male presented with dyspnea, hemoptysis, and chest pain.
- Diagnostic workup revealed deep venous thrombosis, lung thromboembolism, and pulmonary artery aneurysms.
Findings:
- The patient received high-dose corticosteroids and six monthly 1-gram pulses of cyclophosphamide.
- Complete regression of pulmonary artery aneurysms and resolution of symptoms were observed.
Implications:
- This case suggests a potential effective treatment regimen for Hughes-Stovin syndrome.
- Aggressive immunosuppressive therapy may halt disease progression and reverse vascular abnormalities.
