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Survival of diabetes patients with major amputation is comparable to malignant disease
Martin Hoffmann1, Peter Kujath2, Annette Flemming3
1University Clinic of Schleswig-Holstein, Luebeck, Germany drmartinhoffmann@gmail.com.
Introduction:
Almost all studies on diabetic foot syndrome focused on prevention of amputation and did not investigate long-term prognosis and survival of patients as a primary outcome parameter.
Methods:
We did a retrospective cohort study including 314 patients who had diabetic foot syndrome and underwent amputation between December 1995 and January 2001.
Results:
A total of 48% of patients received minor amputation (group I), 15% only major amputation (group II) and 36% initially underwent a minor amputation that was followed by a major amputation (group III). Statistically significant differences were observed in comparison of the median survival of group I to group II (51 vs. 40 months; p = 0.016) and of group II to group III (40 vs. 55 months; p = 0.003).
Discussion:
The prognosis of patients with major amputation due to diabetic foot syndrome is comparable to patients with malignant diseases. Vascular interventions did not improve the individual prognosis of patients.
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