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Subglottic laryngitis--Changes in therapy approach over the past 20 years
Ana Penezić1, Mirko Ivkić2, Boris Ivkić1
1Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center "Sisters of Mercy", Vinogradska cesta 29, 10000 Zagreb, Croatia.
Management of subglottic laryngitis in Croatia has evolved significantly. Racemic epinephrine use increased, while humidification, antibiotics, and antihistamines decreased, with corticosteroids remaining key for moderate cases.
Area of Science:
- Pediatric Otolaryngology
- Respiratory Medicine
- Clinical Practice Guidelines
Background:
- Subglottic laryngitis management has seen shifts in therapeutic approaches over two decades.
- Understanding these changes is crucial for optimizing pediatric respiratory care.
Purpose of the Study:
- To analyze the evolution of subglottic laryngitis treatment strategies in Croatia from 1993 to 2013.
- To identify key changes in the management of moderately severe subglottic laryngitis.
Main Methods:
- A questionnaire-based survey was distributed to pediatricians and otolaryngologists in Croatian hospitals in 1993, 2003, and 2013.
- Respondents reported on their management of a standardized case of subglottic laryngitis and hospital practices.
- Trend analysis using the Cochran-Armitage test assessed changes in treatment over time (p<0.05).
Main Results:
- Racemic epinephrine use dramatically increased (pediatricians: 17.2% to 100%; ENTs: 3.3% to 92.3%).
- Humidification, antibiotic, and antihistamine use significantly declined.
- Corticosteroids (parenteral and nebulized) remained a consistent and central treatment modality.
Conclusions:
- Key changes in subglottic laryngitis management include increased racemic epinephrine use and decreased reliance on humidification, antibiotics, and antihistamines.
- Corticosteroids continue to be the cornerstone therapy for moderately severe cases.
- Therapeutic approach disparities between pediatricians and otolaryngologists have diminished over the 20-year period.
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