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Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
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Is There Any Association between PEEP and Upper Extremity DVT?
Farah Al-Saffar1, Ena Gupta1, Furqan Siddiqi2
1Department of Medicine, University of Florida College of Medicine, Jacksonville, FL 32209, USA.
Critical Care Research and Practice
|April 30, 2015
Summary
Positive end-exploratory pressure (PEEP) does not increase the risk of upper extremity deep vein thrombosis (UEDVT). Congestive heart failure is a risk factor, while longer mechanical ventilation duration decreases UEDVT risk.
Area of Science:
- Critical Care Medicine
- Vascular Surgery
- Pulmonary Medicine
Background:
- Positive end-exploratory pressure (PEEP) is a mechanical ventilation setting that may theoretically increase venous stasis.
- Upper extremity deep vein thrombosis (UEDVT) is a serious complication in critically ill patients.
Purpose of the Study:
- To investigate the association between PEEP levels and the incidence of UEDVT.
- To identify risk factors for UEDVT in mechanically ventilated patients.
Main Methods:
- Retrospective case-control study of 112 medical intensive care unit patients.
- Patients required mechanical ventilation for over 72 hours and underwent duplex ultrasound for suspected DVT.
- Data collected included PEEP levels, duration of mechanical ventilation, and patient comorbidities.
Main Results:
- The incidence of UEDVT was 28.5% (32/112 patients).
- Congestive heart failure (CHF) was significantly associated with increased UEDVT risk (OR 4.53).
- Longer duration of mechanical ventilation (≥13 days) was associated with a reduced risk of UEDVT (OR 0.29).
- No association was found between PEEP levels and UEDVT incidence.
Conclusions:
- PEEP is not associated with an increased risk of UEDVT.
- CHF is a significant risk factor for UEDVT.
- Prolonged mechanical ventilation may have a protective effect against UEDVT.
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