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The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from...
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The large intestine hosts the most densely populated microbial ecosystem in the human body. This complex community primarily consists of anaerobic bacteria, with Bacillota (formerly Firmicutes) and Bacteroidota (formerly Bacteroidetes) as the predominant groups. The distribution of these microbes varies along different sections of the large intestine, influenced by local environmental factors such as oxygen availability and nutrient composition.The cecum, located at the beginning of the large...
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Selection in the host structures the microbiota associated with developing cod larvae (Gadus morhua).

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The marine fish larval microbiota is distinct from its environment and changes significantly with age. Host selection, driven by gut development, shapes these bacterial communities.

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Area of Science:

  • Marine biology
  • Microbiology
  • Genomics

Background:

  • Marine fish larvae host diverse bacterial communities.
  • Larval microbiota may be influenced by unique environmental factors compared to terrestrial animals.

Purpose of the Study:

  • To analyze the beta-diversity of cod larval microbiota.
  • To compare larval microbiota with water and live feed bacterial communities.
  • To understand the factors structuring marine fish larval microbiota.

Main Methods:

  • Pyrosequencing of bar coded v4 16S rDNA amplicons.
  • Analysis of beta-diversity in microbial communities.
  • Comparison of larval, water, and live feed microbiota.

Main Results:

  • Cod larval microbiota composition changed significantly with age.
  • Larval microbiota was distinct from water and live feed, especially early on.
  • Microbiota similarity to water increased with larval age.

Conclusions:

  • Host selection strongly structures the cod larval microbiota.
  • Changes in microbiota are linked to the development of the larval intestinal system.
  • Non-stochastic processes influence microbial community structure in marine larvae.