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Fatty acid and phospholipase A2 plasma levels in children with autism
Márcia Helena Fávero de Souza Tostes1, Hudson Caetano Polonini2, Rosemeri Mendes2
1Núcleo de Pesquisa e Inovação em Ciências da Saúde, Universidade Federal de Juiz de Fora, Juiz de Fora, MG, Brazil.
Objective:
To evaluate fatty acid plasma levels, phospholipase A2 activity, and the developmental profiles of children with autism vs. control subjects.
Methods:
Twenty four children with autism underwent laboratory analysis for fatty acid quantification using gas chromatography and PLA2 activity determination by fluorometric assay.
Results:
No correlation was observed between the developmental quotient and fatty acid plasma levels. Phospholipase A2 activity was significantly higher among autistic children compared with controls.
Conclusion:
The study did not show a correlation between fatty acid and phospholipase A2 plasma levels and the developmental profile of children with autism.
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