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Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
Insights
Untreated Lyme disease can cause Lyme carditis, affecting up to 10% of patients with heart issues ranging from mild disturbances to severe heart failure. Early suspicion is key, even without a tick bite history, for prompt diagnosis and treatment.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Case Reports
Background:
- Lyme disease, a tick-borne illness, can manifest cardiac complications in up to 10% of infected individuals.
- Cardiac involvement in Lyme disease (Lyme carditis) presents a spectrum of clinical severity, from asymptomatic conduction abnormalities to life-threatening arrhythmias and heart failure.
Observation:
- A history of tick bite or Erythema migrans is often absent in patients with Lyme carditis, complicating early diagnosis.
- Cardiac symptoms necessitate a high index of suspicion in patients from endemic areas with potential Lyme disease exposure.
Findings:
- This report details a case of Lyme carditis presenting with varying degrees of atrioventricular block.
- A review of existing literature on Lyme carditis is included to provide further context.
Implications:
- Clinicians should maintain a low threshold for suspecting Lyme carditis in at-risk populations, irrespective of classic exposure markers.
- Prompt recognition and management of Lyme carditis are crucial to prevent severe cardiac sequelae and improve patient outcomes.
Abstract:
Untreated Lyme disease can affect the heart in up to 10% of patients. Its clinical outcome and severity vary, ranging from asymptomatic minor conduction disturbances to potentially fatal arrhythmias and severe heart failure. A history of a tick bite or a typical previous skin lesion (Erythema migrans) may be absent; clinicians should therefore keep a low threshold of suspicion when facing cardiac manifestations in a patient potentially exposed to the disease in endemic areas. We report the case of a patient with Lyme carditis expressed by variable degrees of atrio-ventricular block and review the literature.
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