Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

1.7K
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
1.7K
Psychosurgery01:30

Psychosurgery

2.4K
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
2.4K
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

2.3K
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
2.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stereoelectroencephalography Electrode Fixation Using a Silicone Electrode Holder.

Operative neurosurgery (Hagerstown, Md.)·2026
Same author

Endoscopic endonasal depth EEG-guided resection of a temporal encephalocele resulting in seizure freedom: illustrative case.

Journal of neurosurgery. Case lessons·2026
Same author

Patient satisfaction and outcomes following shave-free craniotomy.

Surgical neurology international·2026
Same author

An Ultra-late Recurrence with Adenoid Cystic Carcinoma-like Malignant Transformation of a Pineal Immature Teratoma after 35 Years: A Case Report.

NMC case report journal·2026
Same author

Successful treatment of aneurysmal subarachnoid hemorrhage in polyarteritis nodosa with immunosuppressive therapy: illustrative case.

Journal of neurosurgery. Case lessons·2026
Same author

Optimization of memory neurofeedback system utilizing intracranial electroencephalogram of the hippocampus.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2025

Related Experiment Video

Updated: Apr 13, 2026

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
06:04

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

1.8K

Epilepsy surgery: current status and ongoing challenges.

Kensuke Kawai1

  • 1Department of Neurosurgery and Epilepsy Center, NTT Medical Center Tokyo.

Neurologia Medico-Chirurgica
|May 1, 2015
PubMed
Summary
This summary is machine-generated.

Surgical treatment for epilepsy, particularly resective surgery for focal epilepsy with lesions, offers satisfactory seizure outcomes. For generalized epilepsies, neuromodulation therapies can help manage seizures when surgery is not an option.

More Related Videos

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
11:29

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

3.2K
Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

13.1K

Related Experiment Videos

Last Updated: Apr 13, 2026

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
06:04

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

1.8K
Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
11:29

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

3.2K
Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

13.1K

Area of Science:

  • Neurosurgery
  • Epileptology
  • Neurology

Background:

  • Epilepsy surgery is a key treatment modality for drug-resistant epilepsy.
  • Advances in surgical techniques and diagnostic tools continue to evolve.
  • Challenges remain in optimizing outcomes for specific epilepsy types.

Purpose of the Study:

  • To review the current state of surgical epilepsy treatments.
  • To highlight ongoing challenges and future directions in epilepsy surgery.
  • To discuss the efficacy of various surgical approaches and neuromodulation.

Main Methods:

  • Review of current literature on epilepsy surgery.
  • Analysis of outcomes for resective, disconnective, and neuromodulation therapies.
  • Discussion of advancements in electroencephalography (EEG) and electrode placement for localization.

Main Results:

  • Resective surgery shows satisfactory seizure outcomes for focal epilepsy with lesions, especially mesial temporal lobe epilepsy.
  • Disconnective surgeries offer comparable or better seizure control with reduced complications.
  • Neuromodulation therapies provide palliative seizure management for generalized or bilateral epilepsies.

Conclusions:

  • Early consideration of surgery for mesial temporal lobe epilepsy is recommended.
  • Further refinement of techniques like multiple subpial transection and hippocampal transection is needed.
  • Improved localization methods and tailored treatment selection are crucial for optimizing epilepsy surgery outcomes.