Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bacterial Gastroenteritis

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A metabolic constraint in de novo NAD+ synthesis drives mucosal inflammation in IBD.

Journal of Crohn's & colitis·2026

Same author

Switch acceptance and persistence of adalimumab biosimilars in IBD patients: a prospective observational study.

Therapeutic advances in gastroenterology·2025

Same author

A Synbiotic Combining Chitin-Glucan and <i>Lactobacillus acidophilus</i> NCFM Induces a Colonic Molecular Signature Soothing Intestinal Pain and Inflammation in an Animal Model of IBS.

International journal of molecular sciences·2024

Same author

Fate of ileorectal anastomosis for treating Crohn's disease in the era of biologics: Results from a French retrospective multicentre cohort study.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2024

Same author

Taxonomic and phenotypic analysis of bifidobacteria isolated from IBD patients as potential probiotic strains.

BMC microbiology·2024

Same author

Should first-line surgery for terminal ileum Crohn's disease be considered?

Journal of visceral surgery·2024

Search research articles

Related Experiment Video

Updated: Apr 13, 2026

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Published on: May 10, 2024

Eosinophilic enteritis.

Guillaume Pineton de Chambrun, Pierre Desreumaux, Antoine Cortot

Digestive Diseases (Basel, Switzerland)

|May 1, 2015

Summary

This summary is machine-generated.

Eosinophilic enteritis, a rare gastrointestinal disorder, presents with diverse symptoms and is linked to allergies. While often benign, some patients experience chronic relapses, requiring targeted therapies.

More Related Videos

Loop-mediated Isothermal Amplification LAMP Assays for the Species-specific Detection of Eimeria that Infect Chickens

Loop-mediated Isothermal Amplification LAMP Assays for the Species-specific Detection of Eimeria that Infect Chickens

Published on: February 20, 2015

Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation

Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation

Published on: June 5, 2012

Related Experiment Videos

Last Updated: Apr 13, 2026

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Published on: May 10, 2024

Loop-mediated Isothermal Amplification LAMP Assays for the Species-specific Detection of Eimeria that Infect Chickens

Loop-mediated Isothermal Amplification LAMP Assays for the Species-specific Detection of Eimeria that Infect Chickens

Published on: February 20, 2015

Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation

Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation

Published on: June 5, 2012

Area of Science:

Gastroenterology
Immunology
Allergy

Background:

Eosinophilic enteritis, a rare primary eosinophilic gastrointestinal disorder (EGID), is characterized by eosinophilic infiltration of the intestinal mucosa.
Its etiology is largely unknown, though allergic triggers are suspected.

Purpose of the Study:

To review the pathogenesis, diagnosis, and treatment of eosinophilic enteritis.
To discuss the clinical presentation and natural history of EGIDs.

Main Methods:

Review of existing literature on eosinophilic enteritis and EGIDs.
Analysis of diagnostic criteria and classification systems.
Summary of current therapeutic approaches.

Main Results:

EGIDs involve complex immune responses, potentially linked to aeroallergens and food allergens.
Diagnosis relies on clinical suspicion due to nonspecific symptoms.
The Klein classification categorizes disease based on the affected gastrointestinal layer.

Conclusions:

Eosinophilic enteritis can be benign but may follow a chronic course with relapses in some patients.
Oral corticosteroids are a primary treatment, with antihistamines and sodium cromoglycate also used.
Further research into EGID mechanisms, including IL-5 and eotaxin, is crucial for targeted therapies.