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Protein and healthy aging.

Douglas Paddon-Jones1, Wayne W Campbell1, Paul F Jacques1

  • 1From the Department of Nutrition and Metabolism, University of Texas Medical Branch, Galveston, TX (DP-J); the Department of Nutrition Science, Purdue University, West Lafayette, IN (WWC); the Jean Mayer USDA Human Nutrition Research Center, Tufts University, Boston, MA (PFJ); Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC (SBK); the Department of Medicine, Boston University, Boston, MA (LLM); the Department of Nutritional Sciences, University of Connecticut, Storrs, CT (NRR); and the NUTRIM School for Nutrition, Toxicology, and Metabolism, Maastricht University, Maastricht, The Netherlands (LJCvL).

The American Journal of Clinical Nutrition
|May 1, 2015
PubMed
Summary
This summary is machine-generated.

Optimizing dietary protein intake, especially at breakfast, can help older adults maintain muscle mass and function. Adequate protein with physical activity may delay sarcopenia and its consequences.

Keywords:
dietary requirementsmusclenutritionproteinsarcopenia

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Area of Science:

  • Gerontology
  • Nutritional Science
  • Muscle Physiology

Background:

  • Sarcopenia, age-related muscle loss, poses significant health challenges for older adults.
  • Current understanding of optimizing dietary protein for healthy aging is evolving.
  • Protein Summit 2.0 highlighted the importance of protein intake timing and quantity.

Purpose of the Study:

  • To explore the benefits of adequate, evenly distributed dietary protein intake for preventing and managing sarcopenia.
  • To discuss the potential of a protein-rich meal pattern, particularly at breakfast, for older adults.
  • To examine the role of leucine and physical activity in muscle protein anabolism.

Main Methods:

  • Literature review and synthesis of current research on protein metabolism and aging.
  • Discussion of protein intake thresholds (e.g., 25-30 g/meal) for muscle health.
  • Analysis of the impact of protein source (animal vs. plant) and leucine content.

Main Results:

  • Consuming adequate high-quality protein at each meal, combined with physical activity, may delay sarcopenia onset and progression.
  • Evenly distributing protein intake throughout the day, including breakfast, supports muscle mass and function.
  • Leucine is a key amino acid for stimulating muscle protein synthesis, with animal proteins generally higher in leucine.

Conclusions:

  • Optimizing dietary protein intake is a promising strategy for healthy aging and sarcopenia prevention.
  • A protein-focused dietary approach, especially targeting lower-protein meals like breakfast, can be beneficial.
  • Further integrated research is needed to fully elucidate the role of dietary protein in aging.