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Updated: Apr 13, 2026

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Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
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[Multiple and simultaneous intracranical hemorrhages with homocysteinemia]
Hikari Sato1, Taro Ohara, Osamu Fukuda
1Department of Neurosurgery, Saito Memorial Hospital.
No Shinkei Geka. Neurological Surgery
|May 1, 2015
Summary
Low intake of colorful vegetables increases homocysteine levels, a risk factor for arteriosclerosis and stroke. This study found a link between high homocysteine and multiple brain hemorrhages, suggesting dietary management is crucial.
Area of Science:
- Neurology
- Cardiovascular Science
- Nutritional Science
Background:
- Homocysteine is linked to arteriosclerosis and cerebral infarction.
- Dietary habits, specifically low intake of colorful vegetables, can elevate homocysteine levels.
Observation:
- Three patients presented with multiple simultaneous intracranial hemorrhages.
- These patients had elevated serum homocysteine levels.
Findings:
- A correlation was observed between homocysteinemia and the development of multiple intracranial hemorrhages.
- Dietary patterns, characterized by reduced colorful vegetable consumption, were identified as a contributing factor to arteriosclerosis and subsequent hemorrhage.
Implications:
- Measuring serum homocysteine is valuable for managing dietary habits and arteriosclerosis progression.
- Early detection and dietary intervention may help prevent intracranial hemorrhages in at-risk individuals.
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