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Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model

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Published on: November 4, 2025

Congenital midline cervical cleft.

Javier Villanueva-Meyer¹, Christine Glastonbury¹, Peter Marcovici¹

¹Department of Radiology and Biomedical Imaging, University of California - San Francisco, San Francisco, California, USA.

Journal of Radiology Case Reports

|May 1, 2015

Summary

This summary is machine-generated.

Congenital midline cervical cleft is a rare newborn condition presenting as a skin band. This case report details its clinical, pathophysiologic, and imaging features in an infant girl.

Keywords:

Congenital midline cervical cleft branchial arch defects congenital midline cervical anomalies midline cervical cleft pediatrics

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Area of Science:

Medical Genetics
Pediatric Surgery
Dermatology

Background:

Congenital midline cervical cleft is a rare congenital anomaly.
It typically manifests in neonates as a suprasternal vertical band of erythematous skin.
A superior nipple-like projection that may exude fluid is characteristic.

Observation:

The anomaly may present with a superior nipple-like projection that can exude fluid.
This report details a case in a newborn girl.

Findings:

The study presents comprehensive clinical and pathophysiologic features.
Imaging findings of this rare entity are also described.

Implications:

This case contributes to the limited literature on congenital midline cervical cleft.
Understanding its presentation aids in early diagnosis and management of rare neonatal conditions.