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Association of systolic dysfunction with left ventricular hypertrophy and diastolic dysfunction in hypertensive

Daniel Piskorz, Laureano Bongarzoni, Luciano Citta

    Revista De La Facultad De Ciencias Medicas (Cordoba, Argentina)
    |May 1, 2015
    PubMed

    Insights

    Systolic dysfunction is common in hypertensive patients with left ventricular hypertrophy (LVH). This dysfunction worsens when diastolic dysfunction (DD) is also present, impacting heart function.

    Area of Science:

    • Cardiology
    • Hypertension Research
    • Echocardiography

    Background:

    • Systolic dysfunction is often unrecognized in patients with hypertension.
    • Left ventricular hypertrophy (LVH) is a common complication of hypertension.

    Purpose of the Study:

    • To demonstrate systolic dysfunction in hypertensive patients with LVH.
    • To show that systolic dysfunction is exacerbated by the presence of diastolic dysfunction (DD).

    Main Methods:

    • Descriptive cross-sectional study with prospective data collection.
    • Evaluation of left ventricular function using conventional echocardiography, mitral inflow Doppler, and tissue Doppler.
    • Patients categorized into four groups based on LVH and DD status.

    Main Results:

    • 292 hypertensive patients were analyzed, categorized by LVH and DD.
    • Patients with DD were older, more often female, and had higher blood pressure.
    • Longitudinal myocardial fiber shortening (s wave) was significantly reduced in patients with both LVH and DD.

    Conclusions:

    • Hypertensive patients with LVH exhibit systolic dysfunction.
    • The severity of systolic dysfunction increases when diastolic dysfunction is also present.
    Abstract

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