Is quantitative diffusion-weighted MRI a valuable technique for the detection of changes in kidneys after

Elif Hocaoglu1, Ercan Inci1, Sibel Aydin2

  • 1Department of Radiology, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.

Abstract

Insights

Diffusion-weighted imaging (DWI) effectively detects kidney changes after extracorporeal shock wave lithotripsy (ESWL), even when ultrasound is normal. This technique aids in predicting potential renal damage from shock waves.

Area of Science:

  • Nephrology
  • Radiology
  • Medical Imaging

Background:

  • Extracorporeal shock wave lithotripsy (ESWL) is a common treatment for renal stones.
  • Assessing kidney injury post-ESWL is crucial for patient management.
  • Conventional imaging like Color Doppler Ultrasonography (CDUS) may not always detect subtle changes.

Purpose of the Study:

  • To evaluate the capability and reliability of diffusion-weighted imaging (DWI) in detecting kidney changes after ESWL.
  • To assess DWI's potential in predicting renal damage following ESWL treatment.

Main Methods:

  • A prospective study of 32 patients undergoing ESWL for renal stones.
  • Diffusion-weighted imaging (DWI) and Color Doppler Ultrasonography (CDUS) performed pre- and post-ESWL.
  • Analysis of Apparent Diffusion Coefficient (ADC) values and Resistive Index (RI) in different kidney regions.

Main Results:

  • Treated kidneys showed statistically significant lower ADC values post-ESWL.
  • Signal intensity at b=1000 s/mm² was the most discriminative parameter.
  • DWI changes were most pronounced in the middle region of treated kidneys (p < 0.01).
  • No significant difference in RI values was observed before and after ESWL.

Conclusions:

  • DWI is a valuable tool for detecting post-ESWL kidney changes.
  • DWI can provide useful information for predicting renal damage, even with normal CDUS findings.
  • This technique enhances the assessment of renal integrity after shock wave lithotripsy.

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