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Is quantitative diffusion-weighted MRI a valuable technique for the detection of changes in kidneys after
Elif Hocaoglu1, Ercan Inci1, Sibel Aydin2
1Department of Radiology, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.
Objective:
The aim of this study was to evaluate the capability and the reliability of diffusion-weighted imaging (DWI) in the changes of kidneys occurring after extracorporeal shock wave lithotripsy (ESWL) treatment for renal stones.
Materials And Methods:
A total of 32 patients who underwent ESWL treatment for renal stone disease between June and December 2011 were enrolled in this prospective study. Color Doppler ultrasonography (CDUS) and DWI were performed before and within 24 hours after ESWL. DWI was obtained with b factors of 0, 500 and 1000 s/ mm2 at 1.5 T MRI. Each of Resistive index (RI) and ADC values were calculated from the three regions of renal upper, middle and lower zones for both of the affected and contralateral kidneys. Paired sample t test was used for statistical analyses.
Results:
After ESWL, the treated kidneys had statistically significant lower ADC values in all different regions compared with previous renal images. The best discriminative parameter was signal intensity with a b value of 1000 s/mm2. The changes of DWI after ESWL were noteworthy in the middle of the treated kidney (p < 0.01). There were no significant difference between RI values in all regions of treated and contralateral kidneys before and after treatment with ESWL (p>0.05).
Conclusion:
DWI is a valuable technique enables the detection of changes in DWI after ESWL treatment that may provide useful information in prediction of renal damage by shock waves, even CDUS is normal.
Insights
Diffusion-weighted imaging (DWI) effectively detects kidney changes after extracorporeal shock wave lithotripsy (ESWL), even when ultrasound is normal. This technique aids in predicting potential renal damage from shock waves.
Area of Science:
- Nephrology
- Radiology
- Medical Imaging
Background:
- Extracorporeal shock wave lithotripsy (ESWL) is a common treatment for renal stones.
- Assessing kidney injury post-ESWL is crucial for patient management.
- Conventional imaging like Color Doppler Ultrasonography (CDUS) may not always detect subtle changes.
Purpose of the Study:
- To evaluate the capability and reliability of diffusion-weighted imaging (DWI) in detecting kidney changes after ESWL.
- To assess DWI's potential in predicting renal damage following ESWL treatment.
Main Methods:
- A prospective study of 32 patients undergoing ESWL for renal stones.
- Diffusion-weighted imaging (DWI) and Color Doppler Ultrasonography (CDUS) performed pre- and post-ESWL.
- Analysis of Apparent Diffusion Coefficient (ADC) values and Resistive Index (RI) in different kidney regions.
Main Results:
- Treated kidneys showed statistically significant lower ADC values post-ESWL.
- Signal intensity at b=1000 s/mm² was the most discriminative parameter.
- DWI changes were most pronounced in the middle region of treated kidneys (p < 0.01).
- No significant difference in RI values was observed before and after ESWL.
Conclusions:
- DWI is a valuable tool for detecting post-ESWL kidney changes.
- DWI can provide useful information for predicting renal damage, even with normal CDUS findings.
- This technique enhances the assessment of renal integrity after shock wave lithotripsy.
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