"Tip-in" technique for retrograde chronic total occlusion revascularization
Related Experiment Video
Updated: Apr 13, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Minh N Vo1, Amir Ravandi, Emmanouil S Brilakis
1Section of Cardiology, St. Boniface Hospital, University of Manitoba, Winnipeg, Canada. mvo@sbgh.mb.ca.
Abstract:
Use of the retrograde approach significantly improves the success rate of chronic total occlusion (CTO) percutaneous coronary intervention. The most commonly applied retrograde technique is placing a guidewire just distal to the distal cap using collateral vessels, with subsequent retrograde crossing of the occlusive segment. This is followed by advancement of a microcatheter and externalization of a long guidewire to allow antegrade delivery of balloons and stents. However, there are occasions when a microcatheter or balloon cannot be delivered retrogradely through the occlusive segment, resulting in procedure failure. We describe the "tip-in" technique, which involves intubation of the retrograde guidewire with an antegrade microcatheter to allow successful revascularization of a CTO after failure to externalize.

