Are there antilymphocyte autoantibodies in multiple sclerosis patients?

Immunoglobulins were separated from sera of 40 multiple sclerosis (MS) patients and 40 healthy controls by density and affinity chromatography. In IgM and IgG fractions of the sera of patients and controls no lymphocyte-specific binding could be detected with the help of FITC-conjugated anti-mu and anti-Fc antibodies.