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Prolonged adrenal insufficiency after unilateral adrenalectomy for Cushing's Syndrome
Bindu Kulshreshtha1, Arpita Arora1, Anshita Aggarwal1
1Department of Endocrinology, PGIMER, Dr. RML Hospital, New Delhi, India.
Abstract:
The contralateral healthy adrenal in patients undergoing unilateral adrenalectomy for Cushing's is known to be suppressed temporarily and forms the basis of peri and postoperative steroids. We present four cases of Cushing's who had prolonged adrenal insufficiency with continued requirement for steroids for periods ranging 1-4 years after unilateral adrenalectomy for Cushing's. We further review literature regarding the recovery of the hypothalamo pituitary adrenal axis postsurgery in patients with Cushing's syndrome.
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